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Medicines That Affect Male Fertility

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                drugs affecting male fertility

Medications are meant to help us out of an already existing physical problem. But sometimes, they also come with side effects or adverse reactions. In some cases, medications, especially hormonal ones are known to cause infertility issues. Don’t panic already, having a few doses won’t cause that much harm. But in the long run, they gradually depreciate sperm quality and lead to infertility issues. Here are some common ones you should be aware of-

medicines affecting fertility in men



Commonly referred to as non-steroidal anti-inflammatory drugs, these include the likes of aspirin and ibuprofen. Now remember that in a limited these medications won’t cause a lot of issues, but in the long run they lower your fertility rates. Especially, the male sperm quality goes down immensely.

Chemo Medicines

All kinds of chemotherapy medications are known to cause an adverse impact on the male fertility rate. These are medicines that are used for treating different kinds of cancer. However, not all forms of chemo therapy may cause reduction in your fertility levels. This usually pertains to the prostrate cancer types mostly.


Commonly used for treating the problem of fluid retention, which is also known as oedema, this medicine causes a temporary reduction in fertility rates. However, in most cases, your sperm and fertility levels tend to resume after a couple of months, once you stop taking spironolactone.


This is an anti-inflammatory drug that is commonly used in treating conditions related to inflammation. These include Crohn's disease (where one sees an inflammation of the intestine) and rheumatoid arthritis (Joint swelling along with pain). Sulfasalazine is known for causing a temporary reduction in sperm count. However, the easier solution here is that once you stop taking the same, the sperm count resumes to normal.

Anabolic steroids

These are steroids that a lot of men resort to for building muscle and increasing levels of endurance and sports performance. However, if the drug is over-used or continued over a longer period, it affects the mobility of the sperms along with reduction in the count.

Herbal remedies

Certain kinds of herbal remedies found commonly like the Tripterygium wilfordii root extract are known to reduce size of the testicles. This is a Chinese herb but it has been used in many herbal medicines too. Along with this, it also slows down sperm growth with regular use.

Do remember that sometimes, you have to take these medicines because of health conditions. However, it is best to always consult a physician before you consume them over a prolonged period, especially if you are trying to have a baby.

posted Feb 24, 2016 by Dr Alok

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